miRNA description for miR-222
miRNA accession miR-222
Species Homo sapiens
 miR-222 identified in exosomes derived from the following tissue/cell type
Adipocytes [Microvesicles] 21435393   
Adipocytes [Microvesicles] 21435393   
Adipocytes [Microvesicles] 21435393   
Breast cancer cells [Exosomes] 33752173   
Breast cancer cells [Exosomes] 33752173   
Breast cancer cells [Exosomes] 33752173   
Breast cancer cells [Exosomes] 33752173   
Dendritic cells [Exosomes] 21505438   
Liver stem cells [Microvesicles] 20668554   
Lung cells [Microvesicles] 20079801   
Mesenchymal stem cells [Microvesicles] 20668554   
Plasma [Microvesicles] 19002258   
Plasma [Exosomes] 33752173   
Plasma [Exosomes] 33752173   
Serum [Exosomes] 18589210   
Serum [Microvesicles] 21435393   
T cells [Exosomes] 21505438   
 Experiment description of studies that identified miR-222 in exosomes
1
Experiment ID206
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 21435393   
OrganismRattus norvegicus
Experiment descriptionMicrovesicles released from rat adipocytes and harboring glycosylphosphatidylinositol-anchored proteins transfer RNA stimulating lipid synthesis
AuthorsMüG, Schneider M, Biemer-Daub G, Wied S.
Journal name Cell Signal
Publication year2011
SampleAdipocytes
Sample nameAdipocytes - Large
Molecules identified in the studymRNA
miRNA
Methods used in the studyRT-PCR
EV-TRACK EV110050: EV-METRIC:43%, 29%
2
Experiment ID207
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 21435393   
OrganismRattus norvegicus
Experiment descriptionMicrovesicles released from rat adipocytes and harboring glycosylphosphatidylinositol-anchored proteins transfer RNA stimulating lipid synthesis
AuthorsMüG, Schneider M, Biemer-Daub G, Wied S.
Journal name Cell Signal
Publication year2011
SampleAdipocytes
Sample nameStromal vascular cells - Differentiated adipocytes
Molecules identified in the studymRNA
miRNA
Methods used in the studyRT-PCR
EV-TRACK EV110050: EV-METRIC:43%, 29%
3
Experiment ID209
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 21435393   
OrganismRattus norvegicus
Experiment descriptionMicrovesicles released from rat adipocytes and harboring glycosylphosphatidylinositol-anchored proteins transfer RNA stimulating lipid synthesis
AuthorsMüG, Schneider M, Biemer-Daub G, Wied S.
Journal name Cell Signal
Publication year2011
SampleAdipocytes
Sample nameAdipocytes - Small
Molecules identified in the studymRNA
miRNA
Methods used in the studyRT-PCR
EV-TRACK EV110050: EV-METRIC:43%, 29%
4
Experiment ID1527
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 33752173   
OrganismHomo sapiens
Experiment descriptionExosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression
AuthorsChen WX, Wang DD, Zhu B, Zhu YZ, Zheng L, Feng ZQ, Qin XH.
Journal name Aging
Publication year2021
SampleBreast cancer cells
Sample nameMCF7 - Adriamycin-resistant
Molecules identified in the studymiRNA
Methods used in the studyRT-PCR
EV-TRACK -
5
Experiment ID1528
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 33752173   
OrganismHomo sapiens
Experiment descriptionExosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression
AuthorsChen WX, Wang DD, Zhu B, Zhu YZ, Zheng L, Feng ZQ, Qin XH.
Journal name Aging
Publication year2021
SampleBreast cancer cells
Sample nameMCF7 - Adriamycin-sensitive
Molecules identified in the studymiRNA
Methods used in the studyRT-PCR
EV-TRACK -
6
Experiment ID1529
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 33752173   
OrganismHomo sapiens
Experiment descriptionExosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression
AuthorsChen WX, Wang DD, Zhu B, Zhu YZ, Zheng L, Feng ZQ, Qin XH.
Journal name Aging
Publication year2021
SampleBreast cancer cells
Sample nameBreast cancer tissue from patients - chemoresistant
Molecules identified in the studymiRNA
Methods used in the studyRT-PCR
EV-TRACK -
7
Experiment ID1530
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 33752173   
OrganismHomo sapiens
Experiment descriptionExosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression
AuthorsChen WX, Wang DD, Zhu B, Zhu YZ, Zheng L, Feng ZQ, Qin XH.
Journal name Aging
Publication year2021
SampleBreast cancer cells
Sample nameBrease cancer tissue from - chemosensitive
Molecules identified in the studymiRNA
Methods used in the studyRT-PCR
EV-TRACK -
8
Experiment ID117
Identified moleculemiRNA
Identification method Human miRNA Microarray Kit
PubMed ID 21505438   
OrganismHomo sapiens
Experiment descriptionUnidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells.
AuthorsMittelbrunn M, Gutiéez-Váuez C, Villarroya-Beltri C, Gonzáz S, Sáhez-Cabo F, Gonzáz MÁ Bernad A, Sáhez-Madrid F.
Journal name NATCOM
Publication year2011
SampleDendritic cells
Sample nameDendritic cells
Molecules identified in the studyProtein
miRNA
Methods used in the studyMass spectrometry
Microarray
EV-TRACK EV110049: EV-METRIC:11%
9
Experiment ID182
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 20668554   
OrganismHomo sapiens
Experiment descriptionMicrovesicles derived from adult human bone marrow and tissue specific mesenchymal stem cells shuttle selected pattern of miRNAs
AuthorsCollino F, Deregibus MC, Bruno S, Sterpone L, Aghemo G, Viltono L, Tetta C, Camussi G.
Journal name PLoS One
Publication year2010
SampleLiver stem cells
Sample nameLiver stem cells - Normal
Molecules identified in the studymiRNA
Methods used in the studyWestern blotting
RT-PCR
Immunogold
Immunoelectron microscopy
EV-TRACK -
10
Experiment ID324
Identified moleculemiRNA
Identification method Microarray or RT-PCR
PubMed ID 20079801   
OrganismMus musculus
Experiment descriptionMicrovesicle entry into marrow cells mediates tissue-specific changes in mRNA by direct delivery of mRNA and induction of transcription
AuthorsAliotta JM, Pereira M, Johnson KW, de Paz N, Dooner MS, Puente N, Ayala C, Brilliant K, Berz D, Lee D, Ramratnam B, McMillan PN, Hixson DC, Josic D, Quesenberry PJ
Journal name Exp Hematol
Publication year2010
SampleLung cells
Sample nameLung cells
Molecules identified in the studyProtein
miRNA
Methods used in the studyFACS
RT-PCR
EV-TRACK EV100071: EV-METRIC:14%
11
Experiment ID181
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 20668554   
OrganismHomo sapiens
Experiment descriptionMicrovesicles derived from adult human bone marrow and tissue specific mesenchymal stem cells shuttle selected pattern of miRNAs
AuthorsCollino F, Deregibus MC, Bruno S, Sterpone L, Aghemo G, Viltono L, Tetta C, Camussi G.
Journal name PLoS One
Publication year2010
SampleMesenchymal stem cells
Sample nameMesenchymal stem cells - Normal
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
RT-PCR
Immunogold
Immunoelectron microscopy
EV-TRACK -
12
Experiment ID175
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 19002258   
OrganismHomo sapiens
Experiment descriptionDetection of microRNA Expression in Human Peripheral Blood Microvesicles
AuthorsHunter MP, Ismail N, Zhang X, Aguda BD, Lee EJ, Yu L, Xiao T, Schafer J, Lee ML, Schmittgen TD, Nana-Sinkam SP, Jarjoura D, Marsh CB
Journal name PLoS One
Publication year2008
SamplePlasma
Sample namePlasma - Normal
Molecules identified in the studymiRNA
Methods used in the studyRT-PCR
EV-TRACK -
13
Experiment ID1531
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 33752173   
OrganismHomo sapiens
Experiment descriptionExosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression
AuthorsChen WX, Wang DD, Zhu B, Zhu YZ, Zheng L, Feng ZQ, Qin XH.
Journal name Aging
Publication year2021
SamplePlasma
Sample nameBreast cancer patients - chemoresistant
Molecules identified in the studymiRNA
Methods used in the studyRT-PCR
EV-TRACK -
14
Experiment ID1532
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 33752173   
OrganismHomo sapiens
Experiment descriptionExosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression
AuthorsChen WX, Wang DD, Zhu B, Zhu YZ, Zheng L, Feng ZQ, Qin XH.
Journal name Aging
Publication year2021
SamplePlasma
Sample nameBreast cancer patients - chemosensitive
Molecules identified in the studymiRNA
Methods used in the studyRT-PCR
EV-TRACK -
15
Experiment ID45
Identified moleculemiRNA
Identification method 467microRNA Array
PubMed ID 18589210   
OrganismHomo sapiens
Experiment descriptionMicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer.
AuthorsTaylor DD, Gercel-Taylor C
Journal name GO
Publication year2008
SampleSerum
Sample nameSerum - Papillary adenocarcinoma of ovary
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
MicroRNA array
EV-TRACK -
16
Experiment ID208
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 21435393   
OrganismRattus norvegicus
Experiment descriptionMicrovesicles released from rat adipocytes and harboring glycosylphosphatidylinositol-anchored proteins transfer RNA stimulating lipid synthesis
AuthorsMüG, Schneider M, Biemer-Daub G, Wied S.
Journal name Cell Signal
Publication year2011
SampleSerum
Sample nameSerum - Normal
Molecules identified in the studymRNA
miRNA
Methods used in the studyRT-PCR
EV-TRACK EV110050: EV-METRIC:43%, 29%
17
Experiment ID115
Identified moleculemiRNA
Identification method Human miRNA Microarray Kit
PubMed ID 21505438   
OrganismHomo sapiens
Experiment descriptionUnidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells.
AuthorsMittelbrunn M, Gutiéez-Váuez C, Villarroya-Beltri C, Gonzáz S, Sáhez-Cabo F, Gonzáz MÁ Bernad A, Sáhez-Madrid F.
Journal name NATCOM
Publication year2011
SampleT cells
Sample nameJ77
Molecules identified in the studyProtein
miRNA
Methods used in the studyMass spectrometry
Microarray
EV-TRACK EV110049: EV-METRIC:11%